Pre-implantation Genetic Testing
Preimplantation genetic testing (PGT) examines embryos during in vitro fertilization (IVF) before possible transfer to a woman’s uterus for a range of genetic problems that can cause implantation failure, miscarriage and birth defects in a resulting child.
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Pre-implantation genetic screening (PGS):
Pre-implantation genetic testing is a last generation genetic test that allows us to screen for chromosomal abnormalities on embryos during an IVF/ICSI cycle. The procedure requires to make a small biopsy on the embryos on which the analysis is performed. Chromosomal abnormalities are a major cause of the failure of embryos to implant, and of miscarriages.
Indications:
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Age over 35 and have a higher risk of having a baby with a chromosome problem (such as Down’s syndrome)
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Have a family history of chromosome problems
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Have a history of recurrent miscarriages
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Several unsuccessful cycles of IVF where embryos have been transferred
Pre-implantation genetic diagnosis (PGD):
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Pre-implantation genetic diagnosis (PGD) enables people with an inheritable condition in their family to avoid passing it on to their children. It involves checking the genes and/or chromosomes of embryos created through IVF.Indications:
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History of previous pregnancies because of a serious genetic condition
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already have a child with a serious genetic condition
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have a family history of a serious genetic condition
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have a family history of chromosome problems
Endometrial receptivity assay (ERA):
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ERA is a personalized genetic test to diagnose the state of endometrial receptivity in the window of implantation. ERA determines the exact time period during which an embryo needs to be transferred into the woman’s uterus to achieve a successful pregnancy.Indication:
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Patients who have had implantation failure with embryos of good morphological quality